منابع مشابه
“ Metathesis in Natural Product Synthesis ”
Institute of Organic Chemistry, Romanian Academy, 202B Spl. Independentei, PO Box 35-108, 060023 Bucharest, Romania; E-mail: *[email protected]; **[email protected] “Metathesis in Natural Product Synthesis” subtitled ‘Strategies, Substrates and Catalysts’ benefits from a foreword by Robert H. Grubbs, joint recipient of the 2005 Nobel Prize in Chemistry for his work on the development of the...
متن کاملRecent applications in natural product synthesis of dihydrofuran and -pyran formation by ring-closing alkene metathesis.
In the past two decades, alkene metathesis has risen in prominence to become a significant synthetic strategy for alkene formation. Many total syntheses of natural products have used this transformation. We review the use, from 2003 to 2015, of ring-closing alkene metathesis (RCM) for the generation of dihydrofurans or -pyrans in natural product synthesis. The strategies used to assemble the RC...
متن کاملNatural Product Synthesis
The Lycopodium alkaloids are a family of structurally complex natural products, which have provoked long-term interests in their total syntheses because of their unique and fascinating architectures and potential biological activities. In particular, fawcettimine-type Lycopodium alkaloids, such as fawcettimine (1) and fawcettidine (2) (Scheme 1), have attracted broad attention from the syntheti...
متن کاملSynthesis of Natural Products and Related Compounds using Enyne Metathesis
Since the molybdenum and ruthenium carbene complexes 1a and 1b were discovered by Schrock and Grubbs in 1990 and 1992, synthetic organic chemistry has progressed with the use of these complexes as the catalyst for olefin metathesis. It was found that the ruthenium carbene complex was also effective for enyne metathesis, which occurs between an alkene and an alkyne. Intramolecular enyne metathes...
متن کاملCascade polycyclisations in natural product synthesis.
The efficient, stereocontrolled construction of polycyclic ring systems has long presented a formidable challenge to synthetic chemists. Cascade reactions offer a 'quick fix'--building multiple rings in a single step--and often dramatically shorten a synthetic route. In this Emerging Area article, a selection of the most recent and impressive examples of applications of this tactic to natural p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Platinum Metals Review
سال: 2011
ISSN: 0032-1400,1471-0676
DOI: 10.1595/147106711x543190